杭州纽罗西敏生物科技有限公司,新型阵列式测序,检测_RT-PCR (一步法 & 二步法)反应体系,肺炎支原体,抗药基因,基孔肯雅,寨卡,登革热,呼吸道病原,粘质沙雷菌,鸟分枝杆菌,嗜麦芽窄食单胞菌,肺炎链球菌,流感嗜血杆菌,博卡病毒,偏肺病毒,流感病毒

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Diabetes following SARS-CoV-2 infection: Incidence, persistence, and implications of COVID-19 vaccination. A cohort study of fifteen million people [ 2023-08-12 ]

Toward a quality-managed operational architecture for wastewater surveillance of zoonotic and emerging pathogens [ 2026-07-11 ]

Isolation and characterization of a clade 2.3.4.4b genotype D1.1 H5N1 virus from dairy cattle in Wisconsin [ 2026-07-11 ]

Highly pathogenic avian influenza A(H5N1) viruses have recently entered U.S. dairy cattle through multiple spillover events from avian reservoirs, creating new opportunities for viral adaptation in mammals. Here, we describe the isolation and characterization of a clade 2.3.4.4b, genotype D1.1 H5N1 virus from bulk milk collected during a spillover event in Wisconsin in December 2025. Phylogenetic analyses demonstrated that this virus represents an independent introduction into dairy cattle distinct from previously reported D1.1 viruses identified in Nevada and Arizona. Although the virus encoded the mammalian-adapting PB2-E627K substitution, it exhibited comparatively low lethality in mice, highlighting the complexity of mammalian adaptation and pathogenicity in H5N1 viruses. These findings expand current understanding of the genetic and phenotypic diversity of H5N1 viruses infecting dairy cattle and emphasize the importance of continued surveillance and functional characterization of emerging strains.

Isolation of Infectious Highly Pathogenic Avian Influenza A(H5N1) Virus from Fetal Bovine Serum, United States, 2025 [ 2026-07-09 ]

In February 2025, we detected highly pathogenic avian influenza virus A(H5N1) clade 2.3.4.4b virus in a fetal bovine serum lot during routine adventitious agent testing. Sequencing confirmed H5N1 genotype B3.13 virus. We found low viral loads in additional samples from the same lot. Heating at 56°C for 30 minutes completely inactivated the virus.

Virome of US bovine calf serum [ 2026-07-09 ]

Using viral metagenomics we analyzed four bovine serum pools assembled from 715 calves in the United States. Two parvoviruses, bovine parvovirus 2 (BPV2) and a previously uncharacterized parvovirus designated as bosavirus (BosaV), were detected in 3 and 4 pools respectively and their complete coding sequences generated. Based on NS1 protein identity, bosavirus qualifies as a member of a new species in the copiparvovirus genus. Also detected were low number of reads matching ungulate tetraparvovirus 2, bovine hepacivirus, and several papillomaviruses. This study further characterizes the diversity of viruses in calf serum with the potential to infect fetuses and through fetal bovine serum contaminate cell cultures.

Artificial intelligence (AI) in action: a cross-continental survey of AI adoption among field epidemiology fellows in Canada, the United States, and Europe, 2024 [ 2026-07-09 ]

Biological Plausibility Assessment of Viral Sequences Generated by a Genomic Language Model [ 2026-07-09 ]

Sialic acids are a barrier to the entry of non-influenza orthomyxoviruses [ 2026-07-09 ]

Mechanisms Underlying the Induction of Immunological Imprinting by RNA Viruses and Intervention Strategies [ 2026-07-08 ]

Viral Pathogen-Specific Severe Acute Respiratory Infections in Hospitalised Adults in Europe: Epidemiological Findings from the id.DRIVE Study 2024–2025 [ 2026-07-08 ]

杭州纽罗西敏生物科技有限公司，您身边的多重PCR专家，专注于新型阵列式测序，检测，分析，流行病学调查平台。

产品展示

PRODUCT SHOW

多重实时PCR反应体系

优化的酶和缓冲溶液系统可用于检测DNA,RNA或cDNA的所有目标

偏肺病毒, 肠道病毒, 博卡病毒多重PCR试剂盒

腺病毒, 鼻病毒, 呼吸道合胞病毒多重PCR试剂盒

副流感病毒1，2，3型多重PCR试剂盒

肺炎链球菌、金黄色葡萄球菌、肺炎衣原体多重PCR试剂盒

直接快速PCR反应体系（血液）

直接快速PCR反应体系（适用于血液样本）

多重, 等位基因特异PCR反应体系

多重等位基因特异PCR反应体系，适合多片段扩增

无宿主DNA PCR反应体系

完全消除酶生产中宿主DNA的污染，最大程度减少假阳性错误

等温扩增试剂盒

使用具有高亲和度的Phi29 DNA 聚合酶

杭州纽罗西敏生物科技有限公司，您身边的多重PCR专家，专注于新型阵列式测序，检测，分析，流行病学调查平台。

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